Metabolic Research

5-Amino-1MQ

NNMT inhibitor · small molecule

Also known as 5-Amino-1-methylquinolinium, 5-AMQ.

A membrane-permeable small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), studied in adipocyte metabolism and NAD+ salvage research.

Current lot: SN-AMQ-2607
Purity: 99.64% by HPLC
Tested: Jul 11, 2026
Stocked in: United States, Canada

Synamino Sciences research vial with a silver cap on a navy background

Ships from

Vial size

$59.00

USD · 50 mg · In stock

Qty

Order by 2:00 PM PT for same-day dispatch from Reno, Nevada. 1–3 business days by USPS Priority and UPS. Free shipping over $150.00.

For laboratory research use only. Not for human or veterinary use.

About the compound

5-Amino-1-methylquinolinium is not a peptide; it is a quinolinium compound that inhibits NNMT, an enzyme that consumes nicotinamide and S-adenosylmethionine. It is used in adipocyte-culture and NAD+ metabolism studies.

Supplied as a lyophilized powder.

Studied inNNMT inhibition · Adipocyte metabolism · NAD+ salvage

Certificate of analysis

The certificate for the lot currently shipping. Every vial in that lot carries the same lot number on its label.

Certificate of analysis

5-Amino-1MQ · 50 mg

Lot SN-AMQ-2607 · tested Jul 11, 2026

99.64%

Purity by HPLC

Labeled: 50 mg
Measured: 50.7 mg
Panel: 6 passed · 2 reported
Laboratory: Independent ISO/IEC 17025 accredited laboratory

Assay	Method	Result	Outcome
Appearance	Visual	White lyophilized powder	Pass
Purity	HPLC · spec ≥ 98%	99.64%	Pass
Net peptide content	HPLC	50.7 mg	Reported
Identity	LC-MS	Confirmed	Pass
Heavy metals	ICP-MS	Not detected	Pass
Sterility	USP <71>	No growth	Pass
Endotoxin	LAL · USP <85>	< 0.05 EU/mL	Reported
Residual solvents	GC-HS	Within limits	Pass

Specification and storage

CAS number: 685079-15-6
Molecular formula: C10H11N2+
Molecular weight: 159.2 g/mol
Reference record: PubChem entry

Storage

Sealed lyophilized vials are stable at room temperature for short periods; store at 2–8 °C for routine use.
For long-term storage keep sealed vials at −20 °C, protected from light and moisture.
Reconstituted solutions should be refrigerated at 2–8 °C and used within the period defined by your laboratory's protocol.

Literature

Peer-reviewed publications on this compound. Provided for reference; they are not claims about this product.

01
Biochemical Pharmacology · 2018
Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice
Neelakantan H, Vance V, Wetzel MD, et al.
02
Journal of Pharmaceutical and Biomedical Analysis · 2021
Development and validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in rat plasma: Application to pharmacokinetic and oral bioavailability studies
Awosemo O, Neelakantan H, Watowich S, et al.
03
Journal of Obstetrics and Gynaecology · 2021
Small molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity in HeLa cells
Akar S, Duran T, Azzawri AA, et al.

Studied alongside

NAD+
Nicotinamide adenine dinucleotide
from $52.00
AOD-9604
hGH fragment 176–191
from $38.00

Research notice

5-Amino-1MQ is supplied for in vitro laboratory research and analytical use by qualified professionals. It is not a medicine, supplement or cosmetic, has not been evaluated by any regulator, and is not for human or veterinary use. Published findings cited on this page are provided for reference and are not claims about this product.